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Federal grants for small businesses
Browse 380 open federal grants for small businesses on grants.gov. See which current opportunities you're eligible for.
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Describe your organization once and Grant Match ranks the open grants below by how well you fit. Free, no account.
Match me to grants →Open grants you may be eligible for
- Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Clinical Centers (U01 Clinical Trial Required)National Institutes of Health · closes Oct 9, 2026
- Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Research Coordinating Center (U24 Clinical Trial Not Allowed)National Institutes of Health · closes Oct 9, 2026
- Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)National Institutes of Health · closes Oct 11, 2026
- NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required)National Institutes of Health · closes Oct 14, 2026
- Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)National Institutes of Health · closes Oct 14, 2026
- NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)National Institutes of Health · closes Oct 14, 2026
- Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)National Institutes of Health · closes Oct 14, 2026
- Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)National Institutes of Health · closes Oct 14, 2026
- Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI) (R01 Clinical Trial Optional)National Institutes of Health · closes Oct 15, 2026
- Maximizing the Scientific Value of Data Generated by the Environmental influences on Child Health Outcomes (ECHO) Program: Dissertation Grant (R36 - Clinical Trial Not Allowed)National Institutes of Health · closes Oct 15, 2026
- CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)National Institutes of Health · closes Oct 16, 2026
- Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)National Institutes of Health · closes Oct 19, 2026
- Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)National Institutes of Health · closes Oct 19, 2026
- Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)National Institutes of Health · closes Oct 22, 2026
- Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)National Institutes of Health · closes Nov 2, 2026
- Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)National Institutes of Health · closes Nov 2, 2026
- Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)National Institutes of Health · closes Nov 5, 2026
- Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)National Institutes of Health · closes Nov 6, 2026
- Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)National Institutes of Health · closes Nov 10, 2026
- Advanced Development and Validation of Emerging Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)National Institutes of Health · closes Nov 10, 2026
- Early-Stage Innovative Technology Development for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)National Institutes of Health · closes Nov 10, 2026
- NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)National Institutes of Health · closes Nov 13, 2026
- NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)National Institutes of Health · closes Nov 13, 2026
- NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)National Institutes of Health · closes Nov 13, 2026
- NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)National Institutes of Health · closes Nov 13, 2026
- Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)National Institutes of Health · closes Nov 16, 2026
- Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)National Institutes of Health · closes Nov 17, 2026
- Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)National Institutes of Health · closes Nov 17, 2026
- NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)National Institutes of Health · closes Nov 17, 2026
- Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R61/R33 Clinical Trial Optional)National Institutes of Health · closes Nov 17, 2026
Grants for small businesses
Federal grants list specific eligible applicant types. This page collects the 380 open opportunities on grants.gov open to small businesses.
Being an eligible applicant type is only the first filter — each grant also has program-specific requirements. Grant Match reads the open opportunities and ranks the ones that fit your organization.
Other applicant types
Other eligible applicantsPublic & state universitiesState governmentsNonprofits with 501(c)(3)Federally recognized tribal governmentsPrivate universitiesCounty governmentsCity or township governmentsNonprofits without 501(c)(3)Special district governments
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